Building GenAI Use Cases in HealthTech: Playbook to Production, Not Just POCs

Discover how HealthTech enterprises can scale GenAI from POCs to production with a 7-step, HIPAA-compliant playbook.

Picture of Edrin Thomas
Edrin Thomas

Founder & CTO

LinkedIn

Table of Contents

Building GenAI Use Cases in HealthTech: Playbook to Production, Not Just POCs

Generative AI (GenAI) has the potential to transform healthcare delivery, from reducing clinician burnout to empowering patients with better experiences. Yet, most HealthTech organizations face a dilemma:

How do we move from pilots and proof-of-concepts (POCs) to scalable, production-grade GenAI systems that are safe, compliant, and effective?

At 10decoders, we’ve seen a clear adoption pattern. Instead of fragmented pilots, healthtech leaders need a structured playbook that balances quick wins with long-term scalability—while meeting HIPAA and regulatory requirements.

In this blog, we present a 7-step playbook that shows how healthcare enterprises can start with retrieval-based assistants and scale all the way to personalized, compliant, and decision-ready AI systems.

Why HealthTech Struggles with GenAI Adoption

  • Compliance Complexity: Data must stay HIPAA-compliant, de-identified, and audit-ready.
  • Fragmented Systems: EMRs, lab reports, insurance documents, and patient data live in silos.
  • Clinical Safety: AI errors can impact lives—so guardrails and human oversight are critical.
  • POC Fatigue: Hospitals and startups build demos but fail to scale to enterprise-wide adoption.

The solution: A systematic playbook that brings healthcare data, personalization, and workflow automation into one GenAI strategy.

The 7-Step Playbook for Building GenAI Use Cases in HealthTech

Step 1: Start with a RAG Foundation

Build a HIPAA-compliant RAG (Retrieval-Augmented Generation) system to centralize healthcare knowledge. 
  • Consolidate EMR data, discharge summaries, and clinical protocols into a GenAI Drive.
  • Provide semantic search and medical FAQ assistants for staff and patients.
  • A hospital chatbot that answers questions about insurance coverage or pre-surgery prep.
Outcome: Clinicians and patients save time retrieving trusted information, reducing staff load.

Step 2: Mature the RAG Layer with Continuous Feedback

Make the RAG assistant clinically reliable.

  • Introduce clinician feedback loops to refine answers.
  • Enhance embeddings with medical ontologies (SNOMED CT, ICD-10, UMLS).
  • Add monitoring dashboards for accuracy, latency, and compliance audit trails.
  • Nurses correcting and validating discharge instructions improves GenAI accuracy over time.

Outcome: A trustworthy medical knowledge hub, continuously improving with clinical validation.

Step 3: Introduce Hyper-Personalization

Deliver AI that adapts to each patient’s unique health journey.

  • Personalize content based on medical history, demographics, and risk profiles.
  • Automate tasks like pre-filled insurance forms, consent forms, or follow-up instructions.
  • A patient with diabetes gets personalized diet recommendations and reminders for lab tests.

Outcome: Patients feel supported with personalized care, and clinicians reduce repetitive tasks.

HealthTech GenAI Maturity Pyramid
HealthTech GenAI Maturity Pyramid

Step 4: Automate Healthcare Workflows with RAG + Personalization

Go beyond answers—automate multi-step healthcare processes.

  • Use RAG + personalization to pre-populate claims forms, referrals, or patient education packets.
  • Automating prior authorization requests by pulling patient history + payer guidelines.
  • Auto-generating physician notes from patient conversations, reducing EHR burden.

Outcome: Clinicians gain more time for patient care, while backend processes run smoother.

Step 5: Bring in the Right Models (Beyond Generic LLMs)

Select healthcare-specific models to maximize safety and accuracy.
  • Use fine-tuned medical LLMs trained on clinical texts.
  • Implement model orchestration for use cases:
    • General Q&A → general-purpose LLM.
    • Clinical summarization → fine-tuned medical model.
    • Imaging + reports → multimodal models.
  • Radiology reports analyzed with a multimodal GenAI model that combines text + scans.
Outcome: Fit-for-purpose AI ensures accuracy, compliance, and trustworthiness in healthcare contexts.

Step 6: Enable Clinical Decision Intelligence

Evolve from workflow automation to supporting decisions.

  • GenAI provides risk predictions, treatment recommendations, and early alerts.
  • AI assistant flags high-risk readmission patients during discharge planning.
  • Always apply human-in-the-loop oversight for clinical safety.

Outcome: Clinicians make better, faster decisions, supported (not replaced) by GenAI.

Step 7: Scale with Governance and GenAI Ops

Operationalize GenAI in a compliant, enterprise-grade way.
  • Implement HIPAA, GDPR, and ethical AI governance.
  • Build MLOps + GenAI Ops pipelines for continuous updates and compliance checks.
  • Audit logs that track every GenAI-generated recommendation for regulators.
  • Establish cross-functional adoption squads: clinicians, compliance, IT, and AI engineers.
Outcome: A scalable, compliant, and sustainable GenAI ecosystem for healthcare enterprises.

Visual Framework: HealthTech GenAI Maturity Playbook

Here’s a suggested diagram design you can use (I can generate a visual for you):

A 7-Layer Pyramid or Funnel Diagram

  • Layer 1: RAG Foundation (Knowledge Assistant)
  • Layer 2: Feedback-Enhanced RAG (Reliable Knowledge Hub)
  • Layer 3: Hyper-Personalization (Patient-Centric AI)
  • Layer 4: Workflow Automation (Healthcare Ops Automation)
  • Layer 5: Fit-for-Purpose Models (Clinical LLMs & Multimodal AI)
  • Layer 6: Clinical Decision Intelligence (Risk + Recommendations)
  • Layer 7: Governance & GenAI Ops (Compliance & Scale)

Each layer builds on the previous one, showing progression from POC → Production → Enterprise-scale AI in HealthTech.

Key Takeaways for HealthTech

  1. Start with a RAG baseline to centralize fragmented clinical and operational data.
  2. Personalization is key—patients and providers must see tangible daily value.
  3. Focus on workflows, not just chatbots—real ROI comes when GenAI automates healthcare processes.
  4. Governance & compliance are mandatory—HIPAA alignment ensures trust.

The goal is production, not pilots—scale responsibly to make GenAI a real clinical partner.

Final Thoughts

The future of healthcare is AI-augmented, not AI-replaced. By following this 7-step journey, HealthTech organizations can transform GenAI from a buzzword into a trusted, compliant, and scalable solution—helping clinicians work smarter, and patients experience more personalized care. At 10decoders, we help healthtech enterprises move from playbooks to production, not just POCs.
Edrin Thomas

Edrin Thomas

Edrin Thomas is the CTO of 10decoders with extensive experience in helping enterprises and startups streamlining their business performance through data-driven innovations

Get in touch

Our Recent Blogs

future-care-driven-by-healthcare-wearables
Healthcare is undergoing a technological revolution. Wearable IoT devices, once considered futuristic, are now actively
Read more ➞
from-sql-server-to-snowflake
Modern enterprises are moving from legacy data warehouses like Microsoft SQL Server to cloud-native platforms
Read more ➞
transforming-healthcare-with-doctor-appointment-apps
Managing healthcare appointments has historically been a time-consuming task, both for patients and providers. Long
Read more ➞